YAP1 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to YAP1.YAP1 is the human ortholog of chicken YAP protein which binds to the SH3 domain of the Yes protooncogeneproduct. YAP1 contains a WW domain that is found in various structural, regulatory andsignaling molecules in yeast, nematode, and mammals, which be involved in protein-proteininteraction. YAP1 is a transcriptional regulator that can act both as a coactivator and a corepressor.YAP1 is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotalrole in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
Product Specifications
Product Name Alternative
Anti-YAP1 antibody, anti-Yorkie homolog antibody, anti-65 kDa Yesassociated protein antibody, anti-YAP65 antibody
UniProt
P46937
Reactivity
Human
Immunogen
N-terminal region of human YAP1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer Biology
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
54
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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