SMARCA5 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to SMARCA5.SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 (SMARCA5) is a member of the SWI/SNF family of proteins. Members of this family have helicaseand ATPase activities and are thought to regulate transcription of certain genes by altering thechromatin structure around those genes. SMARCA5 is a component of the chromatin remodeling andspacing factor RSF, a facilitator of the transcription of class II genes by RNA polymerase II. It hasbeen shown that SMARCA5 is overexpressed in CD34-positive erythrocyte progenitor cells in acutemyeloid leukemia, while its down-regulation correlates with hematologic remission followingchemotherapy.
Product Specifications
Product Name Alternative
UniProt
O60264
Reactivity
Human, Mouse
Immunogen
N-terminal region of human SMARCA5
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
122
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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