AGO1 (N1) Antibody, Rabbit Polyclonal
Rabbit polyclonal to AGO1.Argonaute1 (AGO1) is also known as Eukaryotic translation initiation factor 2C 1 (EIF2C1), which is amember of the Argonaute family of proteins that play a role in RNA interference. AGO1 is highly basic, and contains a PAZ domain and a PIWI domain. It may interact with dicer1 and play a role in shortinterfering-RNA-mediated gene silencing. AGO1 binds to short RNAs such as microRNAs (miRNAs) or short interfering RNAs (siRNAs), and represses the translation of mRNAs complementary to them.AGO1 lacks endonuclease activity and does not appear to cleave target mRNAs. AGO1 is alsorequired for transcriptional gene silencing (TGS) of promoter regions which are complementary tobound short antigene RNAs
Product Specifications
Product Name Alternative
UniProt
Q9UL18
Reactivity
Human
Immunogen
N-terminal region of human AGO1
Clonality
Polyclonal
Conjugation
Unconjugated
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
97
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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