RPL5 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to RPL5.Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large60S subunit. Together these subunits are composed of 4 RNA species and approximately 80structurally distinct proteins. RPL5 is a component of the 60S subunit that belongs to the L18P familyof ribosomal proteins. RPL5 is located in the cytoplasm and binds 5S rRNA to form a stable complexcalled the 5S ribonucleoprotein particle NP), which is necessary for the transport of nonribosomeassociatedcytoplasmic 5S rRNA to the nucleolus for assembly into ribosomes. RPL5 interactsspecifically with the beta subunit of casein kinase II. Variable expression of RPL5 in colorectalcancers compared to adjacent normal tissues has been observed, although no correlation betweenthe level of expression and the severity of the disease has been found.