KLRG1 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to KLRG1.Killer cell lectin-like receptor subfamily G member 1 (KLRG1) is a single-pass type II cell membraneprotein that is expressed specifically on natural killer (NK) cells and activated CD8 T-cells and isinduced by pathogens and viral infections. KLRG1 forms monomer and disulfide-linked homodimer.KLRG1 plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to theirnon-MHC ligands. KLRG1 may mediate missing self recognition by binding to a highly conserved siteon classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 andR-cadherin/CDH4 on target cells.
Product Specifications
Product Name Alternative
UniProt
O88713
Reactivity
Human, Mouse
Immunogen
C-terminal region of mouse KLRG1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
21
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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