KDM7 (M) Antibody, Rabbit Polyclonal
Rabbit polyclonal to KDM7.Lysine-specific histone demethylase 7 (KDM7) is a histone demethylase required for braindevelopment. KDM7 specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 andH3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20' residue (H4K20Me1), thereby playing a central role in histone code. KDM7 specifically binds trimethylated'Lys-4' of histone H3 (H3K4me3), affecting histone demethylase specificity: in presence of H3K4me3, it has no demethylase activity toward H3K9me2, while it has high activity toward H3K27me2.
Product Specifications
Product Name Alternative
UniProt
Q6ZMT4
Reactivity
Human
Immunogen
Middle region of human KDM7
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
107
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
IP, WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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