KDM4A (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to KDM4A.Lysine-specific demethylase 4A (KDM4A) is a histone demethylase that specifically demethylates 'Lys-9' and 'Lys-36' residues of histone H3, thereby playing a central role in histone code. KDM4A does not demethylate histone H3 'Lys-4', H3 'Lys-27' nor H4 'Lys-20'. KDM4A demethylates trimethylated H3 'Lys-9' and H3 'Lys-36' residue, while it has no activity on mono-and dimethylated residues. KDM4A has been shown to participate in transcriptional repression of ASCL2 and E2F-responsive promoters via the recruient of histone deacetylases and NCOR1, respectively.
Product Specifications
Product Name Alternative
UniProt
O75164
Reactivity
Human
Immunogen
C-terminal region of human KDM4A
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Metabolism Research
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
121
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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