RBBP8 (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to RBBP8.RBBP8 is a DNA endonuclease that cooperates with the MRN complex in processing meiotic andmitotic double-strand breaks by ensuring both resection and intrachromosomal association of thebroken ends. RBBP8 promotes ATR and RPA recruient to DSBs in S/G2 phase and facilitates thegeneration of ssDNA. RBBP8 may modulate the functions ascribed to BRCA1 in transcriptionalregulation, DNA repair, and/or cell cycle checkpoint control.
Product Specifications
Product Name Alternative
UniProt
Q99708
Reactivity
Human, Mouse
Immunogen
N-terminal region of human RBBP8
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
102
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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