PARP (N) Antibody, Rabbit Polyclonal
Rabbit polyclonal to PARP.Poly [ADP-ribose] polymerase 1 (PARP) is involved in the base excision repair (BER) pathway bycatalyzing the poly (ADP-ribosyl) ation of a limited number of acceptor proteins involved in chromatinarchitecture and in DNA metabolism. This modification follows DNA damages and appears as anobligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks. PARPpositively regulates the transcription of MTUS1 and negatively regulates the transcription ofMTUS2/TIP150.
Product Specifications
Product Name Alternative
UniProt
P09874
Reactivity
Human
Immunogen
N-terminal region of human PARP
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cancer, DNA Damage, Epigenetics
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
113
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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