TNF-α Chimeric Mouse-Human Monoclonal Antibody

<strong>TNF-α Chimeric Mouse-Human Monoclonal Antibody </strong>_x000D_ <strong>Catalog number:</strong> B2017695_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> DIF, Differentiation-inducing Factor, TNFA, TNFSF2, Tumor Necrosis Factor-α_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Tumor Necrosis Factor Antagonists 2017 Feb 10. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–._x000D_ 2: Siegel SA, Shealy DJ, Nakada MT, Le J, Woulfe DS, Probert L, Kollias G, Ghrayeb J, Vilcek J, Daddona PE. The mouse/human chimeric monoclonal antibody cA2 neutralizes TNF in vitro and protects transgenic mice from cachexia and TNF lethality in vivo Cytokine. 1995 Jan;7(1):15-25._x000D_ 3: Ye Q, Wang Z, Li Y, Wang S, Zhou H, Zhu H, Lei P, Liu L, Shen G. The effect of anti-TfR mouse/human chimeric antibody on anti-transplant rejection Transpl Int. 2011 Feb;24(2):167-74._x000D_ 4: Knight DM, Trinh H, Le J, Siegel S, Shealy D, McDonough M, Scallon B, Moore MA, Vilcek J, Daddona P, et al. Construction and initial characterization of a mouse-human chimeric anti-TNF antibody Mol Immunol. 1993 Nov;30(16):1443-53._x000D_ 5: Scallon BJ, Moore MA, Trinh H, Knight DM, Ghrayeb J. Chimeric anti-TNF-alpha monoclonal antibody cA2 binds recombinant transmembrane TNF-alpha and activates immune effector functions Cytokine. 1995 Apr;7(3):251-9._x000D_ 6: Calabrese LH. Molecular differences in anticytokine therapies Clin Exp Rheumatol. 2003 Mar-Apr;21(2):241-8._x000D_ 7: CDP 571: anti-TNF monoclonal antibody, BAY 103356, BAY W 3356, Humicade Drugs R D. 2003;4(3):174-8._x000D_ 8: Nagahira K, Fukuda Y, Nasu T, Kawashima H, Noguchi C, Kurihara T, Oikawa S, Nakanishi T. Construction and expression of a mouse-human chimeric antibody against human tumor necrosis factor-alpha Immunol Lett. 1998 Dec;64(2-3):139-44._x000D_ 9: Lorenz HM, Kalden JR. Perspectives for TNF-alpha-targeting therapies Arthritis Res. 2002;4 Suppl 3(Suppl 3):S17-24._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/15013927">10: Toussirot E, Wendling D. The use of TNF-alpha blocking agents in rheumatoid arthritis: an overview Expert Opin Pharmacother. 2004 Mar;5(3):581-94. </a>_x000D_ _x000D_ <strong>Products Related to TNF-α Chimeric Mouse-Human Monoclonal Antibody can be found at</strong> <a href="https://moleculardepot.com/product-category/Antibodies/"> Antibodies</a>