BMI1 (C) Antibody, Rabbit Polyclonal
Rabbit polyclonal to BMI1.BMI1 is a component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required tomaintain the transcriptionally repressive state of many genes, including Hox genes, throughoutdevelopment. PcG PRC1 complex acts via chromatin remodeling and modification of histones; itmediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in itsexpressibility. In the PRC1 complex, BMI1 is required to stimulate the E3 ubiquitin-protein ligaseactivity of RNF2/RING2.
Product Specifications
Product Name Alternative
UniProt
P35226
Reactivity
Human, Mouse
Immunogen
C-terminal region of human BMI1
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
37
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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