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PIAS3 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to PIAS3.Protein inhibitor of activated STAT3 (PIAS3) is a member of the PIAS proteins. The mammalian PIASfamily is composed of four proteins: PIAS1, PIAS2 (PIASx), PIAS3, and PIAS4 (PIASy) . PIAS proteinsfunction as E3 small ubiquitin-like modifier (SUMO) ligases, which facilitate the conjugation of SUMOto the specific protein substrates. PIAS3 has been shown to play important roles in the transcriptionalregulation of various cellular pathways, including STAT, SMAD and the steroid hormone signalingpathways. The effects of this transcriptional co-regulation, transactivation or silencing, may varydepending upon the biological context.

Product Specifications

Product Name Alternative

Anti-PIAS3 antibody, anti-Protein inhibitor of activated STAT protein 3 antibody

UniProt

O88907

Reactivity

Human, Mouse

Immunogen

C-terminal region of mouse PIAS3

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics

Dilution

WB:1:1000-1:5000

Purity

Affinity purification

Molecular Weight

68

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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