PIAS1 (C) Antibody, Mouse Monoclonal
Mouse monoclonal to PIAS1.PIAS1 is a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator oftranscription) ] family of transcriptional modulators. PIAS1 functions as an E3 small ubiquitin-likemodifier (SUMO) ligase. It stabilizes the interaction between UBE2I and the substrate, and functionsas a SUMO-tethering factor. PIAS1 plays an important role in the transcriptional regulation ofnumerous cellular pathways, including STAT, NFkB, p53 and the steroid hormone signalingpathways. Recent studies revealed that PIAS1 is an important regulator for innate immunity, inflammatory cytokine signaling and regulatory T cell differentiation.
Product Specifications
Product Name Alternative
UniProt
P49763
Reactivity
Mouse
Immunogen
C-terminal region of mouse PIAS1
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Cancer, Developmental Biology, Epigenetics
Dilution
WB:1:1000-1:5000
Purity
Caprylic Acid-Ammonium Sulfate precipitation
Molecular Weight
72
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Mouse
Preservative
0.02% Thimerosal
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human BSD domain-containing protein 1 (BSDC1)
Recombinant Human BSD domain-containing protein 1 (BSDC1)
Recombinant Human BSD domain-containing protein 1 (BSDC1)
Recombinant Human BSD domain-containing protein 1 (BSDC1)
Recombinant Human BSD domain-containing protein 1 (BSDC1)