CD86 (N) Antibody, Mouse Monoclonal
Mouse monoclonal to CD86.T-lymphocyte activation antigen CD86 is a receptor involved in the costimulatory signal essential forT-lymphocyte proliferation and interleukin-2 production. CD86 binds to CD28 or CTLA-4 and may playa critical role in the early events of T-cell activation and costimulation of naive T-cells, such asdeciding between immunity and anergy. CD86 isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regulator of T-cell activation.
Product Specifications
Product Name Alternative
UniProt
P42081
Reactivity
Human
Immunogen
N-terminal region of human CD86
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:5000
Purity
Caprylic Acid-Ammonium Sulfate precipitation
Molecular Weight
38
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Mouse
Preservative
0.02% Thimerosal
Frequently Asked Questions
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