IL-17A (N) Antibody, Mouse Monoclonal
Mouse monoclonal to IL17A.IL-17A is a proinflammatory cytokine produced by activated T cells. IL-17A is found both in glycosylated and nonglycosylated forms. IL-17A regulates the activities of NF-kappaB and mitogen-activated protein kinases, and it can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO) . High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Product Specifications
Product Name Alternative
Anti-Interleukin 17A antibody, anti-Cytotoxic Tlymphocyteassociated antigen 8 antibody, anti-CTLA8 antibody, anti-IL17 antibody
UniProt
Q16552
Reactivity
Human
Immunogen
N-terminal region of human IL-17A
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Immunology & Inflammation
Dilution
WB:1:1000-1:5000
Purity
Caprylic Acid-Ammonium Sulfate precipitation
Molecular Weight
17.5
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
ELISA, WB
Host or Source
Mouse
Preservative
0.02% Thimerosal
Frequently Asked Questions
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