Adenosine 5′-diphosphoribose

Adenosine 5′-diphosphoribose (ADP ribose) is composed of an adenine base attached to a ribose sugar, which is in turn linked to two phosphate groups. Adenosine 5′-diphosphoribose is a key molecule involved in a variety of cellular processes, particularly in the response to DNA damage and the regulation of gene expression[1].

Product Specifications

CAS Number

[20762-30-5]

Product Name Alternative

ADP ribose

UNSPSC

12352005

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/adenosine-5-diphosphoribose.html

Purity

98.21

Solubility

H2O : 175 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](O)[C@H](N2C=NC3=C2N=CN=C3N)O[C@@H]1COP(OP(OC[C@H]([C@H]([C@H](C=O)O)O)O)(O)=O)(O)=O

Molecular Formula

C15H23N5O14P2

Molecular Weight

559.32

References & Citations

[1]Gibson BA, et al., New insights into the molecular and cellular functions of poly (ADP-ribose) and PARPs. Nat Rev Mol Cell Biol. 2012 Jun 20;13 (7) :411-24.