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N- (4-Carboxycyclohexylmethyl) maleimide

N- (4-Carboxycyclohexylmethyl) maleimide is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

64987-82-2

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-4-carboxycyclohexylmethyl-maleimide.html

Purity

97.0

Solubility

DMSO : ≥ 200 mg/mL

Smiles

O=C(C1CCC(CN2C(C=CC2=O)=O)CC1)O

Molecular Formula

C12H15NO4

Molecular Weight

237.25

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Available Sizes

Frequently Asked Questions

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