PEG-bis-amine (MW 8000)

PEG-bis-amine (MW 8000) synthesizes folate-conjugated polymeric micelles for encapsulation of the anticancer agent 9-nitrocamptothecin HY-16560 (HY-16560) . Folic acid-conjugated polymer micelles are effective carriers of insoluble anticancer drugs, which can avoid macrophages and play a role in endocytosis of tumor cells mediated by folate receptors (FR) .

Product Specifications

CAS Number

[24991-53-5]

Product Name Alternative

Poly (ethylene glycol) -bis-amine (MW 8000)

UNSPSC

12352200

Hazard Statement

H315, H317, H318, H334

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/peg-bis-amine-mw-8000.html

Purity

97.0

Solubility

10 mM in DMSO

Smiles

NCCOCCOCCN.[n]

Molecular Formula

(C2H4O) nC4H12N2O

Molecular Weight

8000 (Average)

Precautions

H315, H317, H318, H334

References & Citations

[1]Han X, et al. 9-NC-loaded folate-conjugated polymer micelles as tumor targeted drug delivery system: preparation and evaluation in vitro. Int J Pharm. 2009 May 8;372 (1-2) :125-31.