Viloxazine (hydrochloride)
Product Specifications
Product Name Alternative
Viloxazin (hydrochloride); Emovit (hydrochloride)
UNSPSC Description
Viloxazine hydrochloride is the hydrochloride salt form of Viloxazine (HY-W380450). Viloxazine (Viloxazin) hydrochloride is a norepinephrine reuptake inhibitor and a potent 5-HT2C agonist agent and 5-HT2B antagonist, EC50 for 5-HT2C b> is 32 μM, and the IC50 for 5-HT2B is 27 μM. Viloxazine hydrochloride's mechanism of action primarily involves serotonergic and noradrenergic pathways. Viloxazine hydrochloride is used in antidepressant research[1][2].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/viloxazine-hydrochloride.html
Purity
98.94
Solubility
DMSO : 33.33 mg/mL (ultrasonic)
Smiles
CCOC1=C(OCC2OCCNC2)C=CC=C1.Cl
Molecular Weight
273.76
References & Citations
[1]Yu C, et al. New Insights into the Mechanism of Action of Viloxazine: Serotonin and Norepinephrine Modulating Properties. J Exp Pharmacol. 2020 Aug 25;12:285-300.|[2]Pinder RM, et al. Viloxazine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1977 Jun;13(6):401-21.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-125784/Viloxazine-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-125784/Viloxazine-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
Launched
CAS Number
35604-67-2
Available Sizes
Curated Selection
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