GLP-1 receptor agonist 7
GLP-1 receptor agonist 7 (Compound 130b) is a potent agonist of glucagon-like peptide-1 (GLP-1) . GLP-1 receptor agonist 7 generates cAMP under the mediation of GLP-1R with an EC50 of ≤ 0.2 nM. GLP-1 receptor agonist 7 can be used to study diseases related to the GLP-1 receptor (particularly type 2 diabetes) [1].
Product Specifications
CAS Number
[2736447-04-2]
UNSPSC
12352005
Target
GLP Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/glp-1-receptor-agonist-7.html
Purity
98.41
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
OC(C1=CC=C2C(N(C(CN3CCC(C4=C(O[C@](C(C=CC(Cl)=C5)=C5F)([H])CO6)C6=CC=C4)CC3)=N2)C[C@@H]7CCO7)=N1)=O
Molecular Formula
C31H30ClFN4O5
Molecular Weight
593.05
References & Citations
[1]Qinghua Meng, et al. Heterocyclic glp-1 agonists. Patent WO2021219019A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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