Aristolactam I (Standard)
Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis[1][2][3][4][5].
Product Specifications
CAS Number
13395-02-3
Product Name Alternative
Aristololactam (Standard) ; Aristolactam (Standard)
UNSPSC
12352005
Target
Apoptosis; Caspase; Reference Standards
Type
Reference Standards
Related Pathways
Apoptosis; Others
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aristolactam-i-standard.html
Smiles
O=C1NC2=C(C3=C4C(C(OC)=CC=C4)=C2)C1=CC5=C3OCO5
Molecular Formula
C17H11NO4
Molecular Weight
293.27
References & Citations
[1]Li J, et al. Toxicities of aristolochic acid I and aristololactam I in cultured renal epithelial cells. Toxicol In Vitro. 2010 Jun;24 (4) :1092-7.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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