TT-10

TT-10 (TAZ-K) is an activator of YES-associated protein (YAP) -transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss[1].

Product Specifications

CAS Number

[2230640-94-3]

Product Name Alternative

TAZ-K

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

YAP

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/tt-10.html

Purity

99.95

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(C1=C(N)N=C(NCC=C)S1)C2=CC=C(F)S2

Molecular Formula

C11H10FN3OS2

Molecular Weight

283.35

Precautions

H302, H315, H319, H335

References & Citations

[1]Masamichi Ito, et al. Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2019 Mar;128:90-95.