TT-10
TT-10 (TAZ-K) is an activator of YES-associated protein (YAP) -transcriptional enhancer factor domain (TEAD) activity. TT-10 can be used for the research of heart diseases accompanied by cardiomyocyte loss[1].
Product Specifications
CAS Number
2230640-94-3
Product Name Alternative
TAZ-K
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/tt-10.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(C1=C(N)N=C(NCC=C)S1)C2=CC=C(F)S2
Molecular Formula
C11H10FN3OS2
Molecular Weight
283.35
Precautions
H302, H315, H319, H335
References & Citations
[1]Masamichi Ito, et al. Characterization of a small molecule that promotes cell cycle activation of human induced pluripotent stem cell-derived cardiomyocytes. J Mol Cell Cardiol. 2019 Mar;128:90-95.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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