Pfn1-IN-1
Pfn1-IN-1 (compound C1) is a Pfn1 inhibitor that inhibits the angiogenic capacity of endothelial cells (EC) . Pfn1 is a regulator of the actin cytoskeleton, inducing actin polymerization and essential cellular activities. Pfn1-IN-1 inhibits Pfn1-Actin interaction and Actin polymerization.
Product Specifications
CAS Number
[919010-46-1]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pfn1-in-1.html
Purity
99.17
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(N=C2N(NN=N2)C3C4=CC=CC(O)=C4)=C3C(C5=CC=C(C)C=C5)=NN1
Molecular Formula
C19H15N7O2
Molecular Weight
373.37
References & Citations
[1]Gau D, et al. Structure-based virtual screening identifies a small-molecule inhibitor of the profilin 1-actin interaction. J Biol Chem. 2018 Feb 16;293 (7) :2606-2616.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
