CEP-1347-acid

CEP-1347-acid is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . CEP-1347-acid can be used for synthesis CEP1347-VHL-02 (HY-168026) [1].

Product Specifications

CAS Number

[874098-83-6]

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cep-1347-acid.html

Smiles

O=C([C@@]1(O)C[C@]2([H])N3C4=CC=C(CSCC)C=C4C5=C3C6=C(C7=CC(CSCC)=CC=C7N6[C@@]1(C)O2)C(CN8)=C5C8=O)O

Molecular Formula

C32H31N3O5S2

Molecular Weight

601.74

References & Citations

[1]Karpińska K, et al. Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC. J Med Chem. 2024 Sep 12;67 (17) :15012-15028.