CEP-1347-acid
CEP-1347-acid is a PROTAC target protein ligand (Ligands for Target Protein for PROTACs) . CEP-1347-acid can be used for synthesis CEP1347-VHL-02 (HY-168026) [1].
Product Specifications
CAS Number
[874098-83-6]
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cep-1347-acid.html
Smiles
O=C([C@@]1(O)C[C@]2([H])N3C4=CC=C(CSCC)C=C4C5=C3C6=C(C7=CC(CSCC)=CC=C7N6[C@@]1(C)O2)C(CN8)=C5C8=O)O
Molecular Formula
C32H31N3O5S2
Molecular Weight
601.74
References & Citations
[1]Karpińska K, et al. Selective Degradation of MLK3 by a Novel CEP1347-VHL-02 PROTAC Compound Limits the Oncogenic Potential of TNBC. J Med Chem. 2024 Sep 12;67 (17) :15012-15028.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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