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Protokylol (hydrochloride)

Protokylol hydrochloride (Caytine hydrochloride; JB-251 hydrochloride) is the hydrochloride salt form of Protokylol. Protokylol hydrochloride is an agonist for β2-adrenergic receptor and TRPV1. Protokylol hydrochloride exhibits activity as a bronchodilator[1].

Product Specifications

CAS Number

136-69-6

Product Name Alternative

Caytine (hydrochloride) ; JB-251 (hydrochloride)

UNSPSC

12352005

Target

Adrenergic Receptor; TRP Channel

Type

Reference compound

Related Pathways

GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/protokylol-hydrochloride.html

Purity

99.07

Solubility

DMSO : 25 mg/mL (ultrasonic) |H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

OC1=CC=C(C(O)CNC(C)CC2=CC=C(OCO3)C3=C2)C=C1O.Cl

Molecular Formula

C18H22ClNO5

Molecular Weight

367.82

References & Citations

[1]Corina Andrei, et al. In Silico Drug Repurposing Framework Predicts Repaglinide, Agomelatine and Protokylol as TRPV1 Modulators with Analgesic Activity. Pharmaceutics. 2022 Nov 22;14 (12) :2563.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

TRPV1; β adrenergic receptor

Available Sizes

Frequently Asked Questions

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