Pentapeptide-3

Pentapeptide-3 is a pentapeptide fragment of neurotoxin waglerin-1, it can be extracted from the venom of Temple Viper. Pentapeptide-3 is a competitive antagonist of nicotinic acetylcholine receptors (nAChRs), it can blocks nerves at the post-synaptic membrane. Pentapeptide-3 has anti-aging effects and it can be used together with other cosmetic peptides[1][2].

Product Specifications

CAS Number

[135679-88-8]

UNSPSC

12352209

Hazard Statement

H302

Target

NAChR

Type

Peptides

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/pentapeptide-3.html

Purity

99.73

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@H]1N(CCC1)C(CN)=O)N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](C)C(N)=O)=O)=O

Molecular Formula

C21H37N9O5

Molecular Weight

495.58

Precautions

H302

References & Citations

[1]Schagen, S.K. Topical peptide treatments with effective anti-aging results. Cosmetics 4 (2), 2017.|[2]Zhmak MN, et al. Peptide inhibitors of nicotinic acetylcholine receptor. WO2014/112902Al, 2017.