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MRP1-IN-1

MRP1-IN-1 (Compound 9h) is a MRP1 inhibitor with an EC50 of 0.90 μM in HeLa-T5 cells[1].

Product Specifications

CAS Number

246238-55-1

UNSPSC

12352005

Target

P-glycoprotein

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mrp1-in-1.html

Smiles

O=C1C2=C(C)ON=C2C3=C(N1C4=CC=CC(CC(NC5=CC(OC)=C(C(OC)=C5)OC)=O)=C4)C=CC=C3Cl

Molecular Formula

C28H24ClN3O6

Molecular Weight

533.96

References & Citations

[1]Norman BH, et, al. Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1) . Bioorg Med Chem Lett. 2002 Mar 25;12 (6) :883-6.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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