MRP1-IN-1
MRP1-IN-1 (Compound 9h) is a MRP1 inhibitor with an EC50 of 0.90 μM in HeLa-T5 cells[1].
Product Specifications
CAS Number
246238-55-1
UNSPSC
12352005
Target
P-glycoprotein
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mrp1-in-1.html
Smiles
O=C1C2=C(C)ON=C2C3=C(N1C4=CC=CC(CC(NC5=CC(OC)=C(C(OC)=C5)OC)=O)=C4)C=CC=C3Cl
Molecular Formula
C28H24ClN3O6
Molecular Weight
533.96
References & Citations
[1]Norman BH, et, al. Tricyclic isoxazoles are novel inhibitors of the multidrug resistance protein (MRP1) . Bioorg Med Chem Lett. 2002 Mar 25;12 (6) :883-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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