Cathepsin B (human, recombinant)

<strong>Cathepsin B (human, recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2017622_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 25 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 37.2 kDa_x000D_ <strong>Supplied as:</strong> POWDER_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -80°C_x000D_ <strong>Keywords:</strong> Amyloid Precursor Protein Secretase, APP Secretase, APPS, Cathepsin B1, CPSB, CTSB, Cysteine Protease_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Prieto Huarcaya S, Drobny A, Marques ARA, Di Spiezio A, Dobert JP, Balta D, Werner C, Rizo T, Gallwitz L, Bub S, Stojkovska I, Belur NR, Fogh J, Mazzulli JR, Xiang W, Fulzele A, Dejung M, Sauer M, Winner B, Rose-John S, Arnold P, Saftig P, Zunke F. Recombinant pro-CTSD (cathepsin D) enhances SNCA/α-Synuclein degradation in α-Synucleinopathy models Autophagy. 2022 May;18(5):1127-1151._x000D_ 2: Moon HY, Becke A, Berron D, Becker B, Sah N, Benoni G, Janke E, Lubejko ST, Greig NH, Mattison JA, Duzel E, van Praag H. Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function Cell Metab. 2016 Aug 9;24(2):332-40._x000D_ 3: Steed PM, Lasala D, Liebman J, Wigg A, Clark K, Knap AK. Characterization of recombinant human cathepsin B expressed at high levels in baculovirus Protein Sci. 1998 Sep;7(9):2033-7._x000D_ 4: Sripa J, Brindley PJ, Sripa B, Loukas A, Kaewkes S, Laha T. Evaluation of liver fluke recombinant cathepsin B-1 protease as a serodiagnostic antigen for human opisthorchiasis Parasitol Int. 2012 Mar;61(1):191-5._x000D_ 5: Puzer L, Cotrin SS, Cezari MH, Hirata IY, Juliano MA, Stefe I, Turk D, Turk B, Juliano L, Carmona AK. Recombinant human cathepsin X is a carboxymonopeptidase only: a comparison with cathepsins B and L Biol Chem. 2005 Nov;386(11):1191-5._x000D_ 6: Rollag H, Mørland B. The effect of recombinant interferons on cathepsin B activity in human monocytes Scand J Rheumatol Suppl. 1988;76:79-83._x000D_ 7: Wang PH, Do YS, Macaulay L, Shinagawa T, Anderson PW, Baxter JD, Hsueh WA. Identification of renal cathepsin B as a human prorenin-processing enzyme J Biol Chem. 1991 Jul 5;266(19):12633-8._x000D_ 8: Ren WP, Fridman R, Zabrecky JR, Morris LD, Day NA, Sloane BF. Expression of functional recombinant human procathepsin B in mammalian cells Biochem J. 1996 Nov 1;319 ( Pt 3)(Pt 3):793-800._x000D_ 9: Norton ES, Whaley LA, Jones VK, Brooks MM, Russo MN, Morderer D, Jessen E, Schiapparelli P, Ramos-Fresnedo A, Zarco N, Carrano A, Rossoll W, Asmann YW, Lam TT, Chaichana KL, Anastasiadis PZ, Quiñones-Hinojosa A, Guerrero-Cázares H. Cell-specific crosstalk proteomics reveals cathepsin B signaling as a driver of glioblastoma malignancy near the subventricular zone bioRxiv [Preprint]. 2023 Aug 21:2023.08.19.553966._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/34546741">10: Song Y, Wright JG, Anderson MJ, Rajendran S, Ren Z, Hua DH, Koehne JE, Meyyappan M, Li J. Quantitative Detection of Cathepsin B Activity in Neutral pH Buffers Using Gold Microelectrode Arrays: Toward Direct Multiplex Analyses of Extracellular Proteases in Human Serum ACS Sens. 2021 Oct 22;6(10):3621-3631. </a>_x000D_ _x000D_ <strong>Products Related to Cathepsin B (human, recombinant) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>