Aristololactam IIIa

Aristololactam IIIa exhibits significant inhibitory effects on superoxide anion generation and elastase release with IC50 values of 0.12 and 0.20 μg/mL, respectively[1].

Product Specifications

CAS Number

[97399-89-8]

UNSPSC

12352005

Target

Elastase

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/aristololactam-iiia.html

Solubility

10 mM in DMSO

Smiles

O=C1NC2=CC3=CC=C(C=C3C4=C2C1=CC5=C4OCO5)O

Molecular Formula

C16H9NO4

Molecular Weight

279.25

References & Citations

[1]Yu-Ming Chung, et al. A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis. Bioorg Med Chem Lett. 2011 Mar 15;21 (6) :1792-4.