Aristololactam IIIa
Aristololactam IIIa exhibits significant inhibitory effects on superoxide anion generation and elastase release with IC50 values of 0.12 and 0.20 μg/mL, respectively[1].
Product Specifications
CAS Number
[97399-89-8]
UNSPSC
12352005
Target
Elastase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/aristololactam-iiia.html
Solubility
10 mM in DMSO
Smiles
O=C1NC2=CC3=CC=C(C=C3C4=C2C1=CC5=C4OCO5)O
Molecular Formula
C16H9NO4
Molecular Weight
279.25
References & Citations
[1]Yu-Ming Chung, et al. A novel alkaloid, aristopyridinone A and anti-inflammatory phenanthrenes isolated from Aristolochia manshuriensis. Bioorg Med Chem Lett. 2011 Mar 15;21 (6) :1792-4.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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