Aminoguanidine (hemisulfate)

Aminoguanidine hemisulfate is an inhibitor of NOS and ROS. Aminoguanidine hemisulfate abolishes ANE-induced ROS production in vitro. Aminoguanidine hemisulfate is used for cancer research[1].

Product Specifications

CAS Number

[996-19-0]

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/aminoguanidine-hemisulfate.html

Purity

99.40

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=S(O)(O)=O.N=C(NN)N.[1/2]

Molecular Formula

CH6N4.1/2H2O4S

Molecular Weight

123.13

Precautions

H302, H315, H319, H335

References & Citations

[1]You-Ting Zhu, et al. Effects of L-arginine on Nitric Oxide Synthesis and Larval Metamorphosis of Mytilus coruscus. Genes (Basel) . 2023 Feb 9;14 (2) :450.|[2]Po-Li Wei, et al. Areca nut extract (ANE) inhibits the progression of hepatocellular carcinoma cells via activation of ROS production and activation of autophagy. Int J Med Sci. 2021 Aug 9;18 (15) :3452-3462.