AChE/BChE-IN-21
AChE/BChE-IN-21 is a histamine H3 receptor antagonist, calcium channel blocker, and acetylcholinesterase inhibitor. AChE/BChE-IN-21 exhibits neuroprotective activity against H2O2 and Aβ1-40, and can restore cognitive function in AD mice[1].
Product Specifications
CAS Number
[2756368-79-1]
UNSPSC
12352005
Target
Amyloid-β; Calcium Channel; Cholinesterase (ChE) ; Histamine Receptor; Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Neuronal Signaling; NF-κB
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-in-21.html
Smiles
O=C(NC(C1=CC=C(OCCCCCN2CCCCC2)C=C1)C(C(OCC)=O)=C3C)N3CCC4CCN(CC4)CC5=CC=CC=C5
Molecular Formula
C38H54N4O4
Molecular Weight
630.86
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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