MMP12-IN-3
MMP12-IN-3 (compound 32) is a potent MMP12 inhibitor with an IC50 value of 4.9 nM. MMP12-IN-3 has the potential for the research of chronic respiratory diseases such as emphysema[1].
Product Specifications
CAS Number
[208663-26-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
MMP
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/mmp12-in-3.html
Purity
99.0
Solubility
10 mM in DMSO
Smiles
CC(C)CC(N(S(=O)(C1=CC=C(OC)C=C1)=O)CC2=CC=CC=C2)C(NO)=O
Molecular Formula
C20H26N2O5S
Molecular Weight
406.50
Precautions
H302, H315, H319, H335
References & Citations
[1]Jeng AY, et al. Sulfonamide-based hydroxamic acids as potent inhibitors of mouse macrophage metalloelastase. Bioorg Med Chem Lett. 1998 Apr 21;8 (8) :897-902.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MMP-12
Available Sizes
Curated Selection
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