Benactyzine hydrochloride

Benactyzine hydrochloride is a competitive BChE inhibitor with a Ki of 0.01 mM. Benactyzine hydrochloride is an anticholinergic drug. Benactyzine hydrochloride has the potential for organophosphate poisoning research[1][2].

Product Specifications

CAS Number

[57-37-4]

UNSPSC

12352005

Hazard Statement

H301, H311, H331

Target

Cholinesterase (ChE)

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Benactyzine_hydrochloride.html

Purity

99.02

Solubility

DMSO : 150 mg/mL (ultrasonic; warming) |H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(OCCN(CC)CC)C(C1=CC=CC=C1)(O)C2=CC=CC=C2.[H]Cl

Molecular Formula

C20H26ClNO3

Molecular Weight

363.88

Precautions

H301, H311, H331

References & Citations

[1]Bodur E, et al. Inhibition effects of benactyzine and drofenine on human serum butyrylcholinesterase. Arch Biochem Biophys. 2001 Feb 1;386 (1) :25-9.|[2]Allikmets LH, et al. Dissimilar influences of imipramine, benactyzine and promazine on effects of micro-injections ofnoradrenaline, acetylcholine and serotonin into the amygdala in the cat. Psychopharmacologia. 1969;15 (5) :392-403.