(R) -Acalabrutinib
(R) -Acalabrutinib ((R) -ACP-196) is the enantiomer of Acalabrutinib. (R) -Acalabrutinib is an inhibitor for Bruton’s tyrosine kinase (BTK).
Product Specifications
CAS Number
1952316-43-6
Product Name Alternative
(R) -ACP-196
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Btk
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-acalabrutinib.html
Solubility
10 mM in DMSO
Smiles
CC#CC(N1[C@H](CCC1)C2=NC(C3=CC=C(C=C3)C(NC4=CC=CC=N4)=O)=C5N2C=CN=C5N)=O
Molecular Formula
C26H23N7O2
Molecular Weight
465.51
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Rayala VVSPK, et al., A validated chiral chromatographic method for the enantiomeric separation of acalabrutinib. Chirality. 2022 Sep;34 (9) :1247-1256.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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