O-DMT-2,2-di (ethoxycarbonyl) propan-1,3-diol
O-DMT-2,2-di (ethoxycarbonyl) propan-1,3-diol is a chemical phosphorylation reagent used for the synthesis of 5'-phosphorylated oligonucleotides. It contains the chemical protective group DMT in its structure, which allows for purification through C18 columns or reversed-phase chromatography[1].
Product Specifications
CAS Number
[171285-25-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
Biochemical Assay Reagents
Type
Oligonucleotides
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/o-dmt-2-2-di-ethoxycarbonyl-propan-1-3-diol.html
Purity
97.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CCCOP(N(C(C)C)C(C)C)OCC(C(OCC)=O)(COC(C1=CC=C(C=C1)OC)(C2=CC=C(C=C2)OC)C3=CC=CC=C3)C(OCC)=O
Molecular Formula
C39H51N2O9P
Molecular Weight
722.80
Precautions
H302, H315, H319
References & Citations
[1]Guzaev A, et al. A new approach for chemical phosphorylation of oligonucleotides at the 5′-terminus[J]. Tetrahedron, 1995, 51 (34) : 9375-9384.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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