N, N-Dicyclohexylcarbodiimide (DCC)

N, N-Dicyclohexylcarbodiimide (DCC) is a dehydrating and condensing agent. N, N-Dicyclohexylcarbodiimide (DCC) enhances adenylate cyclase activity. N, N-Dicyclohexylcarbodiimide (DCC) inhibits amine accumulation. N, N-Dicyclohexylcarbodiimide (DCC) is used to prepare 3-phenylcoumarin derivatives, sulfated derivatives of purslane polysaccharides[1][2][3][4][5][6].

Product Specifications

CAS Number

[538-75-0]

UNSPSC

12352200

Hazard Statement

H302, H311, H317, H318

Target

Adenylate Cyclase; Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

GPCR/G Protein; Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-n-dicyclohexylcarbodiimide-dcc.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C1(N=C=NC2CCCCC2)CCCCC1

Molecular Formula

C13H22N2

Molecular Weight

206.33

Precautions

H302, H311, H317, H318

References & Citations

[1]Suchi R, et al. Covalent modification of the amine transporter with N, N'-dicyclohexylcarbodiimide. Biochemistry. 1991 Jul 2;30 (26) :6490-4.|[2]Azulai R, et al. Uncoupling of gonadotropin-sensitive adenylate cyclase by N, N'-dicyclohexylcarbodiimide. Evidence for modification of two sites. Mol Cell Endocrinol. 1980 Apr;18 (1) :1-10.|[3]Al-Sheddi ES, et al. Novel all trans-retinoic Acid derivatives: cytotoxicity, inhibition of cell cycle progression and induction of apoptosis in human cancer cell lines. Molecules. 2015 May 7;20 (5) :8181-97.|[4]Chen T, et al. Sulfated modification and cytotoxicity of Portulaca oleracea L. polysaccharides. Glycoconj J. 2010 Aug;27 (6) :635-42.|[5]Sashidhara KV, et al. Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents. Bioorg Med Chem Lett. 2011 Apr 1;21 (7) :1937-41.|[6]Kim KS, et al. Oral Nanoparticles Exhibit Specific High-Efficiency Intestinal Uptake and Lymphatic Transport. ACS Nano. 2018 Sep 25;12 (9) :8893-8900.