Tazemetostat de (methylene morpholine) -O-C3-O-C-COOH
Tazemetostat de (methylene morpholine) -O-C3-O-C-COOH (Compound 21b) incorporates a ligand for EZH2, and a PROTAC linker, which recruit E3 ligases. Tazemetostat de (methylene morpholine) -O-C3-O-C-COOH (Compound 21b) can be used for the research of lymphoma[1].
Product Specifications
CAS Number
[2750350-39-9]
UNSPSC
12352005
Target
Histone Methyltransferase; Target Protein Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
Epigenetics; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tazemetostat-de-methylene-morpholine-o-c3-o-c-cooh.html
Purity
99.06
Solubility
DMSO : ≥ 160 mg/mL
Smiles
O=C(COCCCOC1=CC=C(C2=CC(C(NCC3=C(C)C=C(C)NC3=O)=O)=C(C)C(N(C4CCOCC4)CC)=C2)C=C1)O
Molecular Formula
C34H43N3O7
Molecular Weight
605.72
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
EZH2
Available Sizes
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