BMS-983970
BMS-983970 is an oral pan-Notch inhibitor for the treatment of multiplecancers[1].
Product Specifications
CAS Number
[1584713-87-0]
UNSPSC
12352005
Target
Notch
Type
Reference compound
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/BMS-983970.html
Concentration
10mM
Purity
99.26
Solubility
DMSO : ≥ 50 mg/mL
Smiles
O=C(N[C@@H]1C(NC2=C(F)C=CC=C2C(C3=CC=CC=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CC4CC4)C(N)=O
Molecular Formula
C26H26F4N4O3
Molecular Weight
518.50
References & Citations
[1]Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer. Cancer Res October 1, 2014 74; 1643.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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