5, 7, 4'-Trimethoxyflavone
5,7,4’-Trimethoxyflavone can be isolated from the medicinal plant Kaempferia parviflora (KP) . 5,7,4’-Trimethoxyflavone is a CFTR activator and EC50 is 64 μM. 5,7,4’-Trimethoxyflavone induces apoptosis, increases proteolytic activation of caspase-3, and degradation of ADP-ribose polymerase (PARP) protein. 5,7,4’-Trimethoxyflavone has antitumor activity. 5,7,4’-Trimethoxyflavone can be used to prevent skin aging and oxidative stress[1][2][3].
Product Specifications
CAS Number
[5631-70-9]
Product Name Alternative
MTF
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Caspase; CFTR; Endogenous Metabolite; PARP
Type
Natural Products
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/5-7-4-trimethoxyflavone.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
COC1=C(C(C=C(C2=CC=C(OC)C=C2)O3)=O)C3=CC(OC)=C1
Molecular Formula
C18H16O5
Molecular Weight
312.32
Precautions
H302, H315, H319, H335
References & Citations
Kaempferia parviflora
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Caspase 3; PARP
Available Sizes
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