O-Me Eribulin
O-Me Eribulin is a derivative of Eribulin and is an ADC cytotoxin that can be used for ADC synthesis. O-Me Eribulin can inhibit the cell viability of SKBR3, MDA-MB-468, and A549 cells, with IC50 values of 0.2052, 0.1827, and 0.5151 nM, respectively. O-Me Eribulin can be used for tumor research[1].
Product Specifications
CAS Number
2676196-81-7
Product Name Alternative
O-Me B1939; O-Me E7389; O-Me ER-086526
UNSPSC
12352203
Target
ADC Payload
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/o-me-eribulin.html
Smiles
C=C1C[C@@](CC[C@@]2(C[C@@]3([H])O4)O[C@]([C@](O[C@](C5)([H])CC6)([H])[C@@]6([H])O7)([H])[C@@]4([H])[C@]7([H])[C@@]3([H])O2)([H])O[C@@]1([H])CC[C@](C[C@@H](C)C8=C)([H])O[C@]8([H])C[C@@](O[C@H](C[C@H](OC)CN)[C@@H]9OC)([H])[C@]9([H])CC5=O
Molecular Formula
C41H61NO11
Molecular Weight
743.92
References & Citations
[1]Sun xing, et al. Drug conjugate of eribulin derivative. CN2022/107479. 2023-01-26.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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