PD 116152
PD 116152 is a phenazine Antibiotic with antimicrobial and antitumor activity. PD 116152 possesses cytotoxic activity against L1210 lymphocytic leukemia and human colon adenocarcinoma (HCT-8) cells with IC50 values of 5.2 x 10-7 M and 7.1 x 10-7 M, respectively. PD 116152 is promising for research of P388 lymphocytic leukemia[1][2].
Product Specifications
CAS Number
101708-64-9
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/pd-116152.html
Smiles
O=CC1=C(C(C)=C(C2=NC3=C(C(OC)=O)C=CC(O)=C3N=C21)O)O
Molecular Formula
C16H12N2O6
Molecular Weight
328.28
References & Citations
[1]Smitka TA, et al. PD 116,152, a new phenazine antitumor antibiotic. Structure and antitumor activity. J Antibiot (Tokyo) . 1986 Jun;39 (6) :800-3.|[2]Tunac J B, et al. PD 116, 152, a novel phenazine antitumor antibiotic discovery, fermentation, culture characterization and biological activity[J]. The Journal of Antibiotics, 1986, 39 (2) : 192-197.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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