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Dexamethasone phosphate (disodium)

Dexamethasone phosphate (Dexamethasone 21-phosphate) disodium is an orally active Glucocorticoid receptor agonist[1].

Product Specifications

CAS Number

[2392-39-4]

Product Name Alternative

Dexamethasone 21-phosphate (disodium)

UNSPSC

12352211

Hazard Statement

H302, H351, H361

Target

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation; Vitamin D Related/Nuclear Receptor

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology

Assay Protocol

https://www.medchemexpress.com/dexamethasone-phosphate-disodium.html

Purity

99.94

Solubility

DMSO : 1 mg/mL (ultrasonic; warming; heat to 80°C) |H2O : ≥ 100 mg/mL

Smiles

O=C1C=C[C@@]2(C)C(CC[C@]3([H])[C@]2(F)[C@@H](O)C[C@@]4(C)[C@@]3([H])C[C@@H](C)[C@]4(O)C(COP(O[Na])(O[Na])=O)=O)=C1

Molecular Formula

C22H28FNa2O8P

Molecular Weight

516.40

Precautions

H302, H351, H361

References & Citations

[1]Fabrizio Bossa, et al. Erythrocytes-mediated delivery of dexamethasone 21-phosphate in steroid-dependent ulcerative colitis: a randomized, double-blind Sham-controlled study. Inflamm Bowel Dis. 2013 Aug;19 (9) :1872-9.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Available Sizes

Curated Selection

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