Dual FAAH/sEH-IN-1
Dual FAAH/sEH-IN-1 (compound 3) is a high affinity dual sEH (soluble epoxide hydrolase) and FAAH (fatty acid amide hydrolase) inhibitor, with IC50 values of 9.6 and 7 nM, respectively. Dual FAAH/sEH-IN-1 shows antinociception against the inflammatory phase[1].
Product Specifications
CAS Number
2756099-59-7
UNSPSC
12352005
Target
Epoxide Hydrolase; FAAH
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/dual-faah-seh-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1CCN(CC1)S(=O)(C2=CC=CC=C2Cl)=O)NC3=CC=C(C=C3)C4=NC5=CC=CC=C5S4
Molecular Formula
C25H22ClN3O3S2
Molecular Weight
512.04
References & Citations
[1]Wilt S, Kodani S, Valencia L, et al. Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. Bioorg Med Chem. 2021;51:116507.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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