Topterone

Topterone is a topical antiandrogen.

Product Specifications

CAS Number

[60607-35-4]

Product Name Alternative

Win 17665

UNSPSC

12352211

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/Topterone.html

Solubility

10 mM in DMSO

Smiles

C[C@@]12[C@@](CCC)(O)CC[C@@]1([H])[C@]3([H])CCC4=CC(CC[C@]4(C)[C@@]3([H])CC2)=O

Molecular Formula

C22H34O2

Molecular Weight

330.50

References & Citations

[1]Ferrari RA, et al. Endocrine profile of topterone, a topical antiandrogen, in three species of laboratory animals. Methods Find Exp Clin Pharmacol. 1980 Apr;2 (2) :65-9.|[2]Chakrabarty K, et al. Mechanism of action of 17 alpha-propyltestosterone in inhibiting hamster flank organ development. J Invest Dermatol. 1980 Jan;74 (1) :5-8.