What is the catalog number for FBXW7 (C) Antibody, Rabbit Polyclonal?

The catalog number for FBXW7 (C) Antibody, Rabbit Polyclonal is orb131883.

What sizes are available for FBXW7 (C) Antibody, Rabbit Polyclonal?

FBXW7 (C) Antibody, Rabbit Polyclonal is available in the following size(s): 100 µL.

Is FBXW7 (C) Antibody, Rabbit Polyclonal in stock?

FBXW7 (C) Antibody, Rabbit Polyclonal is currently made to order / not held in immediate stock. Contact us for lead time.

FBXW7 (C) Antibody, Rabbit Polyclonal

Rabbit polyclonal to FBXW7. F-box/WD repeat-containing protein 7 (FBXW7) is a substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. FBXW7 probably recognizes and binds to phosphorylated target proteins. Furthermore, FBXW7 is involved in the degradation of cyclin-E, MYC, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1.

Product Specifications

Product Name Alternative

Anti F-box/WD repeat-containing protein 7 antibody, anti Archipelago homolog antibody, anti hAgo antibody, anti F-box and WD-40 domaincontaining protein 7 antibody, anti F-box protein FBX30 antibody, anti SEL-10 antibody, anti hCdc4 antibody, anti FBW7 antibody, anti FBX30 antibody, anti SEL10 antibody

UniProt

Q969H0

Reactivity

Human

Immunogen

C-terminal region of human FBXW7

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Concentration

100 μg/ml BSA

Dilution

WB:1:1000-1:3000

Purity

Affinity purification

Molecular Weight

80

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Applications Notes

WB: The apparent protein size on WB may be different from the calculated M.W. due to modifications.Experiment Notes: Rabbit polyclonal antibodies were produced by immunizing animals with a GST-fusion protein containing the C-terminal region of human FBXW7.