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XRCC4 (N) Antibody, Rabbit Polyclonal

Rabbit polyclonal to XRCC4. DNA repair protein XRCC4 is involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V (D) J recombination. XRCC4 binds to DNA and to DNA ligase IV (LIG4) . The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.

Product Specifications

Product Name Alternative

Anti DNA repair protein XRCC4 antibody, anti X-ray repair cross-complementing protein 4 antibody

UniProt

Q13426

Reactivity

Human, Mouse

Immunogen

N-terminal region of human XRCC4

Clonality

Polyclonal

Conjugation

Unconjugated

Field of Research

Epigenetics & Chromatin

Purity

Affinity purification

Molecular Weight

38

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Tested Applications

IP, WB

Host or Source

Rabbit

Preservative

0.01% NaN3

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