SMND-309
SMND-309 is a metabolite of salvianolic acid B, and exhibits neuroprotective effects in cultured neurons and in permanent middle cerebral artery occlusion rats[1][2].
Product Specifications
CAS Number
1065559-56-9
UNSPSC
12352005
Target
Drug Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/SMND-309.html
Purity
97.12
Solubility
DMSO : ≥ 3.7 mg/mL
Smiles
OC1=C(C(/C=C/C(O)=O)=CC=C1O)/C(C(O)=O)=C\C2=CC(O)=C(C=C2)O
Molecular Formula
C18H14O8
Molecular Weight
358.30
References & Citations
[1]Hou J, Tian J, Jiang W, Gao Y, Fu F.
 Therapeutic effects of SMND-309, a new metabolite of salvianolic acid B, on experimental liver fibrosis.
 Eur J Pharmacol. 2011 Jan 10;650 (1) :390-5.|[2]Yang J, Zhang G, Tian J, Li C, Jiang W, Xing Y, Zhu H, Hou J, Xu H, Wu J.
 Cardioprotective effect of SMND-309, a novel derivate of salvianolic acid B on acute myocardial infarction in rats.
 Basic Clin Pharmacol Toxicol. 2010 Apr;106 (4) :317-23.|[3]Wang Y, Zhang J, Han M, et al. SMND-309 promotes neuron survival through the activation of the PI3K/Akt/CREB-signalling pathway. Pharm Biol. 2016;54 (10) :1982-1990.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
HP220791 200 Reactions
LOC146489 Human qPCR Primer Pair (XM_047734)
Sign In for Pricing
View Details 
AP23303PU-N 100 µg
C Reactive Protein (CRP) (N-term) Rabbit Polyclonal Antibody
Sign In for Pricing
View Details 
