EZH2 (M) Antibody, Rabbit Polyclonal
Rabbit polyclonal to EZH2.Enhancer of zeste homolog 2 (EZH2) belongs to the Polycomb-group (PcG) family. Members from this family form multimeric protein complexes, which play a role in maintaining the transcriptional repressive state of genes over successive cell generations. EZH2 interacts with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. The complex it forms with EED/PRC2 promotes the methylation of Lys-9 and Lys-27 of histone H3, which in turn leads to the transcriptional repression of the target genes.
Product Specifications
Product Name Alternative
UniProt
Q15910
Reactivity
Human
Immunogen
Middle region of human EZH2
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Epigenetics & Chromatin
Dilution
WB:1:1000-1:5000
Purity
Affinity purification
Molecular Weight
85
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Tested Applications
WB
Host or Source
Rabbit
Preservative
0.01% NaN3
Frequently Asked Questions
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